Brazil’s Health Regulatory Agency (Anvisa) has ordered the recall of Magnésio L-Treonato 1000 mg, a dietary supplement sold by Natural Sempre Distribuidora e Comércio Ltda., after finding that its main compound is not authorized for that category in Brazil.
The measure, announced on Monday, June 1, also suspends the product’s manufacture, distribution, advertising, sale and use. Anvisa said the order applies to all lots of the supplement.
Why Anvisa Acted
According to Anvisa, the product was being marketed as a dietary supplement containing magnesium threonate. The agency said that ingredient is not approved under Brazilian rules for use in dietary supplements.
Brazil regulates supplements through a list of permitted ingredients and conditions of use. A 2021 sanitary alert circulated by Santa Catarina’s state health surveillance agency, citing Anvisa, said only constituents authorized under Anvisa’s 2018 rules and later updates may be used in food supplements. The same alert stated that L-threonate of magnesium was not authorized for that purpose.
Anvisa’s latest decision was published in Brazil’s Official Gazette through Resolution RE No. 2,135/2026. The official notice identified the company as Natural Sempre Distribuidora e Comércio Ltda., CNPJ 50.747.962/0001-47.
What Consumers Should Do
G1 and Olhar Digital reported that consumers who bought the supplement should stop using it and seek guidance from the company’s customer-service channels or from local health surveillance authorities.
The reports said Anvisa’s resolution did not mention adverse-event reports or documented harm linked to the product. The decision was based on a regulatory irregularity: the use of a compound not allowed in Brazil’s dietary-supplement category.
Natural Sempre had not responded to requests for comment from G1 and Olhar Digital at the time of their reports.
A Broader Enforcement Pattern
Magnesium threonate is commonly promoted in advertising and on social media as a form of magnesium associated with brain health, memory and cognition. Anvisa’s action does not evaluate those marketing claims in the reports reviewed; it addresses whether the ingredient may legally be used in supplements sold in Brazil.
The issue is not new. In 2021, Anvisa alerted state-level health surveillance bodies about irregular supplements made with L-threonate of magnesium and asked inspectors to take appropriate measures when companies selling such products were identified.
In July 2025, Agência Brasil reported a separate Anvisa enforcement action involving several products, including one identified as L-Treonato de Magnésio. In that case, the product was linked to a different company, Grupo Nutra Nutri Ltda., which the report said lacked Anvisa operating authorization, and the products lacked registration, notification or listing with the agency.
The latest recall is narrower: it targets Natural Sempre’s Magnésio L-Treonato 1000 mg and all of its lots. But it reflects the same regulatory position Anvisa has maintained for years: magnesium threonate is not authorized as a dietary-supplement ingredient in Brazil.